I have been using Windows Vista for some months now, and I am still getting to see new cool things that I like.

I won’t go into depth, but the latest and coolest two things that I found are:

1. Hold down SHIFT and then right click on a file in Windows Explorer – then you’ll see a new item on the contextual menu called: “Copy as Path” – yeah finally this is supported natively by the OS :D The print screens below show the contextual menu without/with holding down shift:Without shift held down:

   

   With shift held down:

   

   You might also notice new items in the contextual menu such as “Pin to Start Menu” and “Add to Quick Launch” – which are also pretty cool, but I don’t tend to use them as often as the “Copy as Path” one :)

2. The second nice thing I found [and which tends to make the "My Favorites" keys on my MM-Keyboard obsolete] is the shortcut combination for the links in the Quick Launch Toolbar.For example if my Quick Launch Toolbar looks like this:

   I can start the Microsoft Internet Explorer by just pressing the Windows Key + 3.

   Generalizing an application from the Quick Launch Toolbar can be started by Windows Key + #, where # is its position number in the Quick Launch Toolbar.

Although simple tricks, these tend to be a couple of the most useful ones I’ve stumbled upon while using Windows Vista.
Hope they’ll help you as much as they are helping me now!